EXAMINE THIS REPORT ON SODIUM PENTOBARBITAL SDS

Check Closely (one)pentobarbital will reduce the extent or effect of fentanyl intranasal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Carefully. Coadministration of fentanyl with CYP3A4 inducers may lead to some lower in fentanyl plasma concentrations, insufficient efficacy or, probably, progress of the withdrawa